IMSI is a refinement of the ICSI process. While standard ICSI involves sperm selection at around 400x magnification, IMSI magnifies sperm up to 6000x. This gives our embryologists the ability to examine fine structural details, such as the shape and presence of vacuoles in the sperm head, which may indicate DNA damage or poor quality.
The aim is to inject the healthiest-looking sperm into the egg, improve fertilisation outcomes and increase the chances of viable embryo development.
The process begins similarly to a regular ICSI cycle. The female partner undergoes ovarian stimulation and egg retrieval. Meanwhile, a semen sample is prepared in the lab. Using a high-powered microscope fitted with digital imaging, our embryologists examine individual sperm at a magnification of 6000x.
This allows us to identify sperm with normal shape, smooth structure and no visible defects. The selected sperm is then injected into a mature egg, just as in ICSI. Fertilised eggs are then cultured and monitored before embryo transfer.
IMSI does not change the overall IVF cycle but enhances the sperm selection process, which can be particularly helpful in challenging cases.
Fertility Doctors in Andhra Pradesh, Telangana & Maharashtra
At KIMS Fertility IVF Centre, we use IMSI to give couples facing sperm-related fertility challenges a higher chance of success. As one of the best fertility centres in the state, we are equipped with high-resolution imaging systems and experienced embryologists trained in advanced sperm selection.
We recommend IMSI only when medically appropriate. Our goal is to tailor treatment plans for each individual or couple and provide options that improve the likelihood of pregnancy without adding unnecessary steps or cost.
IMSI is often recommended in the following situations:
IMSI provides an added level of selection for couples who may not have seen results with conventional ICSI.
